Clinical manifestations. Primary infection caused by a virus Varicella – Zoster (VZV), manifested wind smallpox. Chickenpox is characterized by generalized itchy rash vezikuleznoy with a small rise in temperature and some systemic symptoms. There are various complications, including bacterial superinfection, thrombocytopenia, arthritis, hepatitis, encephalitis or meningitis, glomerulonephritis. In some cases, wind smallpox developing Reye syndrome. In children with immunodeficiency disease can progress. This is repeated continuing rash and high fever in the second week of illness. Some children with immunodeficiency develop encephalitis, pancreatitis, hepatitis and pneumonia. A heavy wind during the smallpox may be in adults. Pneumonia, which is rarely in healthy children is a common complication in elderly persons.
Following primary infection the virus exists in latent form. Enabling it manifests itself in the form of denying opoyasyvayuschego. Grouped puzyrkovye rash apply to 1-3 dermatoma sensitive and sometimes accompanied by pain, localized in this area. Systemic symptoms are minor. When immune deficiency shingles sometimes becomes generalized, with lesions that appear from the outside dermatitis, and visceral disorders.
Fetal intrauterine infection may occur embriopatiey, which is characterized by scarring of the skin, limbs and extremities atrofiey. There may also see manifestations of the central nervous system and eyes. Congenital syndrome sometimes develops after the wind smallpox from the mother in the first or early second trimester of pregnancy. The children who had prenatal contact with the VZV, sometimes there shingles at the very beginning of life, without previous wind smallpox. Chickenpox from a newborn may develop in connection with the illness prior to the birth mother.