Diagnostic significance is fourfold or more increase in titer of serum agglutinin to the F. tularensis, which occurs after the second week of illness, and confirms the diagnosis. A one-time positive result in credits 1:160 or higher indicates a fresh or previously rescheduled disease. Probirochnye tests are more reliable than the plate. There are false positive results agglutination test reactions to F. tularensis, as it provides a cross-agglutination with antibodies to Brucella, Proteus and geterofilnymi antibodies. By contracting guinea pigs, or in special environments agent can be extracted from blood, skin separating ulcers, punktatov affected lymph nodes, stomach wash water and sputum.
Laboratory should be informed of the suspected tularemia, because the allocation of crops has limited the choice of growth media, and the bacteriological studies represent a potential risk of infection of laboratory personnel. Perhaps the detection of antigen in the fluid that separates ulcers and punktatah bubonic immunoflyuorestsentsii indirect method, though not always have the opportunity to conduct these studies.
Treatment. The usual treatment is streptomycin for 7-10 days. Gentamicin is also effective. The use of alternative medicines – tetracycline (which should not give children under 9 years old) or chloramphenicol does not exclude the probability of clinical relapses.
The isolation of hospitalized patients. It should be careful when dealing with separable or secret until not stop the allocation of losses.
The control measures. 1. Those at risk should be limited to the minimum biting insects by using protective clothing, frequent inspections and removing ticks from the skin and Hair Loss head. Use repellents also be useful.
2. Children are prohibited care or play with sick or dead rabbits and rodents.
3. When you work with wild rabbits and other potentially infected animals should wear rubber gloves.
4. The meat of wild rabbits should be carefully prozharivat or provarivat.
5. The masks for the face and rubber gloves must be worn to those working with cultures or infected materials in the laboratory. When using zagryazennymi things should also be careful.
6. Any shipment of infected animals.
7. All those who frequently come into contact with an agent, including Fellows laboratories recommended immunization weakened live vaccine (available at the Centers for disease Control).