There are currently 1 percent solution of silver nitrate, 0.5-percent solution of erythromycin or 1 percent solution of tetracycline entered the local and equally acceptable to the prevention of eye gonoreynoy infection in newborns. Silver nitrate is considered and the best way, where often penitsillinazoprodutsiruyuschie Neisseria gonorrhoeae (I’I'NG), and published data on the effectiveness of prevention eritromitsinovoy not available, and only one study has shown the effectiveness of preventive application of tetracycline in this area with high frequency PPNG infection. In the United States, where frequent hlamidialnaya infection and it has received greater attention than gonokokkovoy infection, are preferable eritromitsinovaya tetratsiklinovaya or ointments. 0.5-percentage Effectiveness eritromitsinovoy ophthalmic ointment in the prevention of neonatal conjunctivitis hlamidialnogo shown in one study, but other works give conflicting results. Chlamydia agents and sensitive to tetracycline, but the study of clinical effectiveness tetratsiklinovoy ointment to prevent hlamidialnyh conjunctivitis are also limited and offer conflicting results. Recent data from Kenya indicate that tetracycline or silver nitrate applied locally, reduce the frequency hlamidialnyh conjunctivitis. And eritromitsinovaya and tetratsiklinovaya ointment is available now in packages containing one dose. Some people prefer eritromitsinovuyu ointment, but the lack of definitive proof of its benefits can not give certain recommendations in choosing a drug for the prevention of neonatal conjunctivitis.