Dental treatment, surgical procedures or instrumental methods, affecting mucous membranes, or surfaces contaminated tissue can cause momentary microbiemia. Portable blood bacteria can settle on the damaged or abnormal heart valves or for endocarditis, some congenital anatomical defects, causing bacterial Endocarditis or endarteriity. However, it is impossible to predict, one of the patients razovetsya the infection or what procedure it would cause. It is therefore recommended that antibiotic prophylaxis for patients at risk who are subjected to interventions, the most likely cause microbiemia. It is important that these antibiotics are given shortly before the procedure, rather than a few days. Some patients (for example, the protezirovannym heart valve or surgical designed system-pulmonalnymi shunt or protokami) are at risk of Endocarditis more than others. Similarly, some dental care (such as extraction) and surgical (eg, urinary-tract sex) procedure more likely than others, cause significant microbiemia. Although it is very difficult to characterize the importance of these factors were taken into account in formulating these recommendations.
Because there is no monitoring of clinical trials, the choice of antibiotics to prevent Endocarditis a person must be based on indirect information. These recommendations are based on a review of available data, including studies in vitro, clinical experience, data from experimental animal models, and evaluation of bacteria, most likely to cause endocarditis. Significant morbidity and mortality in the Infectious Endocarditis and lack of monitoring of clinical observations indicate the need for continuing research on epidemiology, pathogenesis, prevention and therapy Endocarditis. Antibiotics used to prevent the recurrence of Urolithiasis is not appropriate for the prevention of bacterial Endocarditis. The additional antibiotics should be prescribed during the procedures associated with the risk of Endocarditis.