Systemic prevention shows where the benefits of preventing wound infection outweighed the risk of reactions to drugs and the emergence of resistant bacteria. The latter represents a potential risk not only for the recipient, but also for other hospital patients, who can develop vnutribolnichnaya infection caused by antibiotikorezistentnymi pathogens. The procedures under which the benefits outweigh the risks of anti-microbial prevention, associated with a significant risk of postoperative infection and in cases where the likelihood of infection may be low, but the complications of infection – catastrophic. The determining factor in the likelihood of surgical infection is the number of microorganisms in the wound after the completion of the transaction. This concept has led to the classification of surgical procedures based on the identification of bacterial pollution and the risk of further infection. Provision 4 broad categories: clean wounds, partly contaminated wound, contaminated wounds and dirty and infected wounds. Within these categories, however, may be significant variations of the risk of infection, which consequently affect the possible need for prevention.
Net wounds. When you clean wounds advantage of systemic antimicrobial prophylaxis is not usually justifies the potential risk associated with the use of antimicrobial drugs, except in circumstances where the consequences of infection can be life threatening, such as the implantation of artificial foreign bodies (such as the introduction of synthetic heart valve), a decline of immune status (such as in patients receiving high-dose corticosteroids or chemotherapy because of malignant tumors) and the opening of body cavity of the newborn. In these cases, prevention is carried out, although the research found that its efficacy is insufficient. Systemic anti-microbial agents empirically recommended for safe surgery in patients with the infection in another part of the body.