Prevention is considered the main cause of inappropriate use of antimicrobial drugs as adults, and children. In 74% of antimicrobial courses, with the aim of preventing in Pennsylvania study, the duration of greater than 48 hours. The advantage of a longer introduction is not proven. In observations of children under 6 years old who have been subjected to surgical operations, from which the application was assessed on the basis of generally accepted guidelines, found that prevention antibiotics used nesootvestvenno 42% of children who received preoperative prophylaxis, 67% of children receive intraoperativnuyu prevention and 55% postoperativnuyu prevention. Around the same university in a large pediatric clinic 66% of antimicrobial drugs used in the surgical department, have been identified as inappropriate for reasons not selected drug dosage, time of application, length and lack of evidence. These findings indicate that the use of antimicrobial funds for children affected by surgery and other invasive procedures should be subject to periodic review.
Guidelines for the application. Studies showing the effectiveness of the system of prevention When infected surgical wounds, were conducted primarily at adults. Because the pathogenesis of these infections in children is the same principles of surgical prophylaxis in children should be similar. In the absence of studies on children leadership, as recommended by the American College of Surgeons – «Medical Letter», the administrative committee of veterans on the application of antimicrobial drugs and the Centers for disease Control, provides the only available standard for the use of systemic prophylactic antibiotics at the pediatric surgical patients.
The following general principles are recommended as a guide with the understanding that research on children may bring some changes and that the factors available only in children, can lead to expulsion.