Anti-microbial agents, in general, appointed in an attempt to prevent infection in children. The effectiveness of prophylactic use of these drugs in certain situations proved, but in most cases insignificant. Chemoprophylaxis is designed for various purposes: to specific pathogens, Infection body affected and vulnerable patients. Effective prevention can be achieved more easily against specific pathogens and certain areas of the body.
Specific agents. Prevention is feasible if the doctor can understand the situation related to increased risk of serious infection caused by a specific agent, and empirically choose antimicrobial, a drug which destroys the causal agent of the probable patients with minimal unwanted effects. For agents, who initially multiply in the upper respiratory tract, elimination of the state carrier may be difficult and requires the use of antibiotics, which effectively penetrates the nasopharyngeal secret, such as rifampin. This property is insufficiently have antibiotics commonly used to treat infections caused by these pathogens.
Affected areas of the body of infection. Prevention of infection susceptible body may be possible if the period of risk determined and short, if the expected stimulus is predictable sensitivity to antibiotics and if the body is achievable for antibiotics.
Protection, created in the urinary tract chemoprophylaxis, mainly depends on the resistance to antibiotics microflora gastrointestinal tract – the normal source of bacteria that fall and bladder. Long-term effectiveness and nitrofurantoina trimetaprimsulfametaksazola explained minimal influence of these drugs pa mikloflory the development of resistance. Both drugs are concentrated in the urine. Thus, an adequate inhibitory effect can be obtained from a lower than usual therapeutic dose. Use one dose of medication at bedtime is enough.
Inflammation of the middle ear occurs less likely to have otitam children, prophylactic treatment with antibiotics. However, studies conducted on a small number of cases and using various medications and methods of evaluation, so the best method is unknown.
Chemoprophylaxis wounds after animal bites is usually not necessary, since only 5% of wounds from dog bites become infected. Prophylaxis is recommended for wounds that can not be adequately cleaned or washed, for deep wounds to the hands and face wounds, where the development of extensive scarring after the infection is totally unacceptable.